What’s new with NDPH?

4 thoughts on “What’s new with NDPH?”

  1. My 14 year old daughter has suffered with NDPH for two years. I’d like to discuss this treatment with her neurologist. Is it available for treatment yet? Please advise.


    1. Hello, sorry to hear about your daughter and her struggle with NDPH, so difficult for kids and families. I do not know where you are located, and I assume you are asking about IV lidocaine. We are only offering it to our patient population in the Boston area. However, you can certainly talk with your neurologist about it and if you are connected to any of the large pediatric headache centers (UCSF, Cleveland clinic, Cincinnati, Mayo Clinic), it might be available and possible there. We are doing a study on NDPH (basic research to gain better understanding, also a study medication) here called Endogenous Modulation and Central Sensitization in New Daily Persistent Headache (NDPH) in Children. If you are interested in participating in this study, you can contact headachestudy@childrens.harvard.edu. Good luck


  2. Hello, my 16 yo son has NDPH. Have your patients with NDPH had success with a keto or low carb diet? There is some evidence to support it’s benefit in migraines, other headaches, seizures, and traumatic brain injury. He has been through many traditional (botox, nerve blocks, SPG, DHE, amitriptyline, supplements, Aimovig,Toradol, Indocin, Topomax, Tizidine, Verapamil, Namenda, Cefaly, and more) and non traditional (CBD, essential oils, NUCCA chiropractic manipulation) treatments that haven’t helped so he’s frustrated and skeptical to start something new that may be difficult but I’m wondering if this diet would be something to consider.


    1. Hello, sorry to hear your son has been struggling with NDPH. He has certainly tried so many meds and treatments. We do recommend some dietary changes to help reduce/resolve NDPH. It is thought that the basis of the headache is an autoimmune/inflammatory response to some sort of stressor, like too many concussions, or a viral illness. For that reason we will suggest an anti-inflammatory diet. There are many resources online for this diet- basically you eliminate foods that tend to be pro-inflammatory (like white flour, sugar, highly processed foods) and eat those that are anti-inflammatory, such as foods rich in Omega 3s, lots of fruits and vegetables, organic meats and eggs, certain whole grains, spices like turmeric, and nuts and seeds. For best evaluation, you need to stay on any diet or supplement for 3 months, and then decide if you are feeling better. Good luck!


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